Thanks for the suggestions.
Motor1.msetup I can see nothing wrong with it.
I can not open the motor setup window, due to the error while the PBrickLV is connected. I attached the motor setup when disconnected.
I also added the troubleshooter errors and warnings.
These screenshots were made with IDE 4.6.3.6.
I set up a completely new PC(Win11) everything set US like (Keyboard, language, home, etc.). I was directly connected to the PBrickLV, so no network based blocking. The firewalls are disabled. I installed everything as admin. I got installation errors the first time (before my first post), when I tried to install it without, as it could not write the global variables. I am the only admin on that PC. There where no errors while installation. I executed the IDE with admin rights.
When I reconnect to the PBrickLV while in the motor setup, I get the a very large error notification. I as not able to copy the text, so I attached it as picture. I hope you can read it, it seems to be scaled down.